Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation
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چکیده
منابع مشابه
03-P075 The repulsive guidance molecule (RGM) family in chicken
anism would thus be a new way to form a tube. As the generation of the lumen and of the tube itself requires the apparition of an apical domain, we decided to investigate how part of the lateral domain becomes apical. Our first results, using transgenes driven by brachyury regulating sequences, show that several proteins classically involved in antero-posterior and planar polarities could be in...
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Repulsive guidance molecule a (RGMa) is a major neuron guidance factor in central nervous systems. We previously found that inhibition of RGMa could greatly enhance neural function rehabilitation in rats after MCAO/reperfusion. Neuron guidance factors are often regulators of angiogenesis. However, the effect of RGMa on angiogenesis and its mechanisms remain to be determined. Here, we investigat...
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BACKGROUND The axons of retinal ganglion neurons from a precise topographic map in the optic tectum in the midbrain, and the guidance of retinal axons by directional cues in the tectum is crucial in this process. Several in vitro systems have been developed in order to identify the molecular basis of these directional cues. Temporal, but not nasal, retinal axons avoid posterior tectal membranes...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2011
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1015605108